Thin layer chromatographic detection of colistin sulfate antibiotic residues in poultry tissues

Residues of antibiotic drugs in food and products have been received much attention recent years because growing safety concerns for public health. There are serious effects residues meat human consumption (e.g., increasing antimicrobial resistance, carcinogenicity, mutagenicity, hypersensitivity). In this study, we used broiler chicks as a laboratory animal to detect the colistin sulfate residue health concerns. The day-old were collected reared up 31 days. treatment was started from day 16th until sacrifice. randomly divided into three groups namely control group (Group A), discriminate B) indiscriminate C) on 14th day. treated with an antibiotic, maintaining withdrawal period one week. case not maintained continued till body weights birds recorded daily. mean weight highest (1261.15±16.37gm) followed by (1156.15±18.23gm) lowest (1008.49±18.11gm). differences among gain statistically significant (P<0.05) compared group. Thin Layer Chromatography revealed that all samples positive Liver, Kidney Spleen, it 100%. except thigh breast muscle percentage Liver sample (66.67%). no results (P<0.05). From above findings, research could be considered need based Bangladesh ascertain influential effect abuse poultry industry.